Frogmative AI

Secure · reviewable · auditable regulatory automation

From study report to a source-linked regulatory record — with expert control.

Frogmative turns study reports into structured, source-linked regulatory drafts ready for expert review and downstream IUCLID workflows. Every prepared value stays tied to its evidence, every decision remains reviewable, and the regulatory expert stays in control.

Study report → source-linked regulatory draft → expert review → contribution or export where supported.

Page of a synthetic toxicology study report used as document input — illustrative synthetic example

Highlighted finding in the synthetic report: the NOAEL sentence with its value marked

Page 18

Frogmative review card: structured key results with stated-in-the-report evidence chips and page references

Illustrative synthetic example — not a real study.

The problem

Regulatory preparation is more than extraction

Extraction alone is not enough. Regulatory teams need traceability, review, controlled export, and confidence that the expert remains responsible for every value.

Manual extraction

Pulling structured fields out of long, inconsistent study reports consumes expert hours that should go to judgment, not transcription.

Traceability

Which value was used, why, and from which page — Frogmative keeps that connection live instead of leaving it to reconstruction later.

IUCLID preparation

Producing consistent, import-ready IUCLID content becomes a reviewed step in the same workflow rather than a separate manual exercise.

Dense synthetic study-report page with narrative text and a results table — illustrative synthetic example — From a dense report page to source-linked, reviewable fields

The same findings as structured Frogmative fields, each carrying its page reference and confidence — From a dense report page to source-linked, reviewable fields

The Frogmative workflow

From PDF to a reviewed record — with expert control

Frogmative document step with an uploaded synthetic study report ready for extraction — 1Study report in— Upload the PDF — preparation starts from the document itself.

Prepared effect-level fields, each with its source page and confidence level — 2Source-linked draft— Every prepared value carries its page reference and confidence.

Review card with key results, evidence chips and the approval controls — 3Expert review— The expert sees the evidence and decides, field by field.

Guided journey panel showing an export-ready study record with completed checks — 4IUCLID-ready— Readiness checks gate contribution and export.

Illustrative synthetic example — not a real study.

Capabilities

Regulatory workflows supported today

Frogmative's deepest current workflow is repeated-dose oral toxicity, including demonstrated IUCLID contribution. Water solubility and aquatic invertebrate acute toxicity already use the same structured extraction and expert-review framework.

Study family	Extraction	Expert review	Validated IUCLID contribution path
Repeated-dose oral toxicity OECD 407/408
Water solubility OECD 105
Aquatic invertebrate acute toxicity OECD 202

A contribution tick means a deployed, validated write-and-read-back pathway exists for that study family. It does not imply that every possible IUCLID destination is automatically populated.

Extract — every value cited to its source passage

Expert review — see, decide and trace every item

Contribute — written to IUCLID and read back for verification

Digital-text and scanned/image-only PDFs are supported within supported Frogmative study workflows.

Evidence discipline

Built around evidence, not generated prose

Source-linked by default

Every prepared value remains connected to the report page and supporting context it came from.

Controlled boundaries

Frogmative distinguishes supported evidence, missing information, uncertainty and expert judgment rather than filling gaps automatically.

Expert authority

Scientific and regulatory judgment stays with the qualified reviewer — nothing is contributed to IUCLID without human review and approval.

The Frogmative evidence drawer: a prepared field with its value, page citation and review controls on the left; the cited page of the synthetic study report open on the right — The evidence drawer: every prepared value opens against the exact source page it cites.Illustrative synthetic example — not a real study.

Security & data handling

Built for regulated workflows

Authenticated, invite-only access

Organisation-level data isolation on every query

Encryption in transit and at rest

Server-side AI processing through Amazon Bedrock — never consumer AI tools

Auditable user and system actions

Explicit controls around source evidence and human approval

Frogmative runs on AWS infrastructure in the UK and Europe, with processing locations documented transparently for customer review.

Detailed security, data-processing and deployment information is available for evaluation and procurement discussions.

Frogmative Expert

A domain-aware regulatory assistant

Frogmative Expert answers toxicology, ecotoxicology, chemistry, IUCLID and regulatory questions inside the authenticated workspace — grounded in the evidence on screen.

Mode-focused for toxicology, ecotoxicology, chemistry and IUCLID
Distinguishes observation from interpretation; points to primary sources
Works alongside the regulated workflow — helping users understand evidence, regulatory context and next actions without bypassing review controls

The Frogmative Expert panel, scoped to the study on screen, answering a dose-justification question with REACH, PPP and BPR framing and a practical recommendation — Frogmative Expert answering inside the review — scoped to the study on screen, advisory only.

See Frogmative on a real study

Start with one supported study and one regulatory expert. The question is simple: does reviewing a source-linked prepared draft beat starting from a blank template?

Start with a public or non-confidential study. Confidential-study engagements follow the relevant security and contracting process.