Secure · reviewable · auditable regulatory automation
Frogmative AI helps regulatory teams turn toxicology study reports into structured, reviewable IUCLID-ready endpoint records. AI drafts the fields, experts approve the evidence, and every decision is audit-logged.
Working vertical slice: repeated-dose oral toxicity → reviewed fields → validated .i6z → ECHA IUCLID Cloud import.
The problem
Extraction alone is not enough. Regulatory teams need traceability, review, controlled export, and confidence that the expert remains responsible for every value.
Pulling structured fields out of long, inconsistent study reports is slow and error-prone.
Which value was used, why, and from which page — hard to evidence and defend later.
Producing consistent, import-valid IUCLID content adds another manual, fragile step.
The Frogmative workflow
Inside Frogmative Workbench
A case holds the source document, the AI extraction, the reviewed fields, exports, and a full audit history. The AI value is never the final value — the reviewed value is.
| Field | AI value | Reviewed value | Conf. | Source | Status |
|---|---|---|---|---|---|
| Guideline | OECD 408 | OECD 409 | high | p.1 | Approved |
| Species | dog | dog | high | p.2 | Approved |
| NOAEL | 0.1 mg/kg bw/day | 0.1 mg/kg bw/day | high | p.9 | Approved |
| LOAEL | 0.5 mg/kg bw/day | 0.5 mg/kg bw/day | high | p.9 | Approved |
| Target system | nervous system | nervous system | medium | p.9 | Approved |
Illustrative panel. The Guideline row shows an expert correction (AI draft → reviewed value).
The approach
Extraction targets a defined toxicology endpoint schema — not free-form chat output.
Every field shows the AI draft, confidence and source page. The expert edits and approves.
Only approved values are exported, and every action is recorded in an audit trail.
Security & data handling
Pilot-grade secure architecture designed for enterprise hardening. We do not claim production certification, blanket zero-retention, or 100% compliance.
What works today
A repeated-dose oral toxicity study (12-month dog study) was processed end-to-end and the generated package imported into the official ECHA IUCLID Cloud as a real endpoint record.
Working vertical slice for one study type — not a full dossier generator yet.
What we need next
See the working vertical slice — secure upload, AI extraction, expert review, validated IUCLID export, and a full audit trail.